Article
Theoretical study of the conformation of the lipoamide arm in a mutant H protein.
Proteins - 15 Nov 2001
Roche O, Field M J
Abstract excerpt
The lipoamide arm of the H protein plays a pivotal role in the catalytic cycle of the glycine decarboxylase complex (GDC) by being successively methylamine loaded (Hmet), reduced (Hred), and oxidized (Hox). In a previous study, we calculated free-energy surfaces as a function of the lipoamide arm position of the three forms of the wild-type protein and found close agreement with the available experimental data....
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