Article
Analysis of integral membrane protein contributions to the deformability and stability of the human erythrocyte membrane.
The Journal of biological chemistry - 14 Dec 2001
Van Dort H M, Knowles D W, Chasis J A, Lee G, Mohandas N, Low P S
Abstract excerpt
Three major hypotheses have been proposed to explain the role of membrane-spanning proteins in establishing/maintaining membrane stability. These hypotheses ascribe the essential contribution of integral membrane proteins to (i) their ability to anchor the membrane skeleton to the lipid bilayer, (ii) their capacity to bind and stabilize membrane lipids, and (iii) their ability to influence and regulate local...
Topics
- 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
- Ankyrins
- Binding Sites
- Biological Transport
- Cell Membrane
- Dimerization
- Eosine Yellowish-(YS)
- Erythrocytes
- Humans
- Immunoglobulin G
- Ions
- Lipid Metabolism
- Phenotype
- Protein Binding
- Time Factors