Article
HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene.
Lancet (London, England) - 3 Jan 1998
Quillent C, Oberlin E, Braun J, Rousset D, Gonzalez-Canali G, Métais P, Montagnier L, Virelizier J L, Arenzana-Seisdedos F, Beretta A
Abstract excerpt
BACKGROUND: Despite multiple exposures to HIV-1, some individuals remain uninfected, and their peripheral-blood mononuclear cells (PBMC) are resistant to in-vitro infection by primary HIV-1 isolates. Such resistance has been associated with a homozygous 32-base-pair deletion (delta 32) in the C-C...
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