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Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4 + and CD8 + T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection

15 Dec 2001

Abstract excerpt

Human immunodeficiency virus (HIV)-specific T-cell responses are thought to play a key role in viral load decline during primary infection and in determining the subsequent viral load set point. The requirements for this effect are unknown, partly because comprehensive analysis of total HIV-specific CD4(+) and CD8(+) T-cell responses to all HIV-encoded epitopes has not been accomplished. To assess these...

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PMID: 11711588
DOI: 10.1128/jvi.75.24.11983-11991.2001

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