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Article

In vivo complex formation of PU.1 with HDAC1 associated with PU.1-mediated transcriptional repression.

Oncogene - 20 Sept 2001

Kihara-Negishi F, Yamamoto H, Suzuki M, Yamada T, Sakurai T, Tamura T, Oikawa T

Abstract excerpt

We previously reported that overexpression of PU.1, a member of the Ets family of transcription factors, induces differentiation inhibition and apoptosis associated with c-Myc down-regulation in murine erythroleukemia (MEL) cells. To understand the molecular mechanism by which c-Myc is down-regulated due to overexpression of PU.1, we performed luciferase reporter assays using the mouse c-myc promoter. PU.1...

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Source

Identifiers

PMID: 11593411
DOI: 10.1038/sj.onc.1204756

Genes

HDAC1
TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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In vivo complex formation of PU.1 with HDAC1 associated with PU.1-mediated transcriptional repression.PMID 11593411Read ↗

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