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Article

Changes in mRNA expression profile underlie phenotypic adaptations in creatine kinase-deficient muscles.

FEBS letters - 28 Sept 2001

de Groof A J, Smeets B, Groot Koerkamp M J, Mul A N, Janssen E E, Tabak H F, Wieringa B

Abstract excerpt

We have studied the mechanisms that regulate the remodeling of the glycolytic, mitochondrial and structural network of muscles of creatine kinase M (M-CK)/sarcomeric mitochondrial creatine kinase (ScCKmit) knockout mice by comparison of wild-type and mutant mRNA profiles on cDNA arrays. The magnitudes of changes in mRNA levels were most prominent in M-CK/ScCKmit (CK(-/-)) double mutants but did never exceed those...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11591374
DOI: 10.1016/s0014-5793(01)02879-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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