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Article

A defect in HIV-1 transgenic murine macrophages results in deficient nitric oxide production.

Journal of leukocyte biology - 1 Oct 2001

Dickie P, Roberts A, Lee R

Abstract excerpt

HIV transgenic mice bearing multiple copies of a noninfectious (Deltagag/pol) proviral DNA were tested for the systemic production of nitric oxide (NO). Serum levels of NO metabolites were reduced about 50% in HIV transgenic mice compared with nontransgenic sibling mice. This difference persisted when NO production was induced with peritoneal injections of bacterial endotoxin (LPS). Peritoneal inflammatory...

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PMID: 11590196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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