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Article

Gene-nutrient and gene-gene interactions of controlled folate intake by Japanese women.

Biochemical and biophysical research communications - 16 Apr 2004

Hiraoka Mami, Kato Kumiko, Saito Yoko, Yasuda Kazuto, Kagawa Yasuo

Abstract excerpt

Elevated serum total homocysteine (tHcy) levels are associated with increased risk for cardiovascular disease and dementia. The prevalence rates of homozygous mutants among Japanese women (n = 300) were 17.3%, 1.3%, 18.6%, and 5.3% for methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C, reduced folate carrier (RFC-1) A80G, and methionine synthase (MS) A2756G, respectively. The tHcy value was...

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Source

Identifiers

PMID: 15044114
DOI: 10.1016/j.bbrc.2004.02.174

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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