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The Herpes Simplex Virus 2 UL21 Protein Is Essential for Virus Propagation

14 Mar 2013

Abstract excerpt

Herpes simplex virus 2 (HSV-2) is an important human pathogen that is the major cause of genital herpes infections and a significant contributor to the epidemic spread of human immunodeficiency virus infections. The UL21 gene is conserved throughout the Alphaherpesvirinae subfamily and encodes a tegument protein that is dispensable for HSV-1 and pseudorabies virus replication in cultured cells; however, its...

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PMID: 23487471
DOI: 10.1128/jvi.03489-12

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The Herpes Simplex Virus 2 UL21 Protein Is Essential for Virus PropagationPMID 23487471Read ↗

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Comparative Analysis of <i>UL16</i> Mutants Derived from Multiple Strains of HSV-2 and HSV-1 Reveals Species-Specific Requirements for the UL16 ProteinSemantic proximity Read ↗

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