Article
The UL25 gene product of herpes simplex virus type 1 is involved in uncoating of the viral genome.
Journal of virology - 1 Jul 2008
Preston Valerie G, Murray Jill, Preston Christopher M, McDougall Iris M, Stow Nigel D
Abstract excerpt
Studies on the herpes simplex virus type 1 UL25-null mutant KUL25NS have shown that the capsid-associated UL25 protein is required at a late stage in the encapsidation of viral DNA. Our previous work on UL25 with the UL25 temperature-sensitive (ts) mutant ts1204 also implicated UL25 in a role at very early times in the virus growth cycle, possibly at the stage of penetration of the host cell. We have reexamined...
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