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Article

Susceptibility gene(s) for Alzheimer's disease on chromosome 10.

Trends in neurosciences - 1 Oct 2001

Lendon C, Craddock N

Abstract excerpt

The majority of Alzheimer's disease is inherited in a complex manner involving environmental factors and several genes. One of these genes is Apolipoprotein E where the polymorphic allele (APOE epsilon 4) has been robustly shown to modify risk and the course of Alzheimer's disease. The epsilon 4 allele however, only accounts for approximately 50% of late onset Alzheimer's disease. Here we review three quite...

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Source

Identifiers

PMID: 11576650
DOI: 10.1016/s0166-2236(00)01912-3

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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