Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Signaling and subcellular localization of the TNF receptor Edar.

Experimental cell research - 1 Oct 2001

Koppinen P, Pispa J, Laurikkala J, Thesleff I, Mikkola M L

Abstract excerpt

Tabby and downless mutant mice have identical phenotypes characterized by deficient development of several ectodermally derived organs such as teeth, hair, and sweat glands. Edar, encoded by the mouse downless gene and defective in human dominant and recessive forms of autosomal hypohidrotic ecto...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ectodysplasins
Share to Edar Receptor
Share to Fluorescent Antibody Technique, Indirect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Nick-End Labeling

Share to Mitogen-Activated Protein Kinases

Share to p38 Mitogen-Activated Protein Kinases

Share to Receptors, Tumor Necrosis Factor

Source

Identifiers

PMID: 11570810
DOI: 10.1006/excr.2001.5331

Genes

TNF
EDA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11570810-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Signaling and subcellular localization of the TNF receptor Edar.PMID 11570810Read ↗

Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar.Semantic proximity Read ↗

Involvement of a novel Tnf receptor homologue in hair follicle induction.Semantic proximity Read ↗

Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis.Semantic proximity Read ↗

Ectodysplasin signaling in development.Semantic proximity Read ↗

TAB2, TRAF6 and TAK1 are involved in NF-kappaB activation induced by the TNF-receptor, Edar and its adaptator Edaradd.Semantic proximity Read ↗

Inducible mEDA-A1 transgene mediates sebaceous gland hyperplasia and differential formation of two types of mouse hair folliclesSemantic proximity Read ↗

Ectodysplasin-A1 is sufficient to rescue both hair growth and sweat glands in Tabby miceSemantic proximity Read ↗

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle developmentSemantic proximity Read ↗

Gene defect in ectodermal dysplasia implicates a death domain adapter in development.Semantic proximity Read ↗

Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice.Semantic proximity Read ↗

The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains.Semantic proximity Read ↗

Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.