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Article

The C terminus of sigma(32) is not essential for degradation by FtsH.

Journal of bacteriology - 1 Oct 2001

Tomoyasu T, Arsène F, Ogura T, Bukau B

Abstract excerpt

A key step in the regulation of heat shock genes in Escherichia coli is the stress-dependent degradation of the heat shock promoter-specific sigma(32) subunit of RNA polymerase by the AAA protease, FtsH. Previous studies implicated the C termini of protein substrates, including sigma(32), as degradation signals for AAA proteases. We investigated the role of the C terminus of sigma(32) in FtsH-dependent...

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Identifiers

PMID: 11566990
DOI: 10.1128/JB.183.20.5911-5917.2001
PMCID: PMC99669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The C terminus of sigma(32) is not essential for degradation by FtsH.PMID 11566990Read ↗

Evidence for an active role of the DnaK chaperone system in the degradation of sigma(32).Semantic proximity Read ↗

Role of region C in regulation of the heat shock gene-specific sigma factor of Escherichia coli, sigma32.Semantic proximity Read ↗

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Conserved region 2.1 of Escherichia coli heat shock transcription factor sigma32 is required for modulating both metabolic stability and transcriptional activity.Semantic proximity Read ↗

A trapping approach reveals novel substrates and physiological functions of the essential protease FtsH in Escherichia coli.Semantic proximity Read ↗

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The C-terminal end of LpxC is required for degradation by the FtsH protease.Semantic proximity Read ↗

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Sequence and length recognition of the C-terminal turnover element of LpxC, a soluble substrate of the membrane-bound FtsH protease.Semantic proximity Read ↗

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