Article
Computer-assisted re-design of spectrin SH3 residue clusters.
Biomolecular engineering - 15 Oct 2001
Angrand I, Serrano L, Lacroix E
Abstract excerpt
We have developed a protein design computer program, called Perla, which performs searches in sequence space to uncover optimal amino acid sequences for desired protein three-dimensional structures. Optimal sequences are localised at the minima of a sequence-structure energy landscape defined usi...
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