Article
Is Ffh required for export of secretory proteins?
FEBS letters - 14 Sept 2001
Kim J, Rusch S, Luirink J, Kendall D A
Abstract excerpt
In Escherichia coli, protein export from the cytoplasm may occur via the signal recognition particle (SRP)-dependent pathway or the Sec-dependent pathway. Membrane proteins utilize the SRP-dependent route, whereas many secretory proteins use the cytoplasmic Sec machinery. To examine the possibility that signal peptide hydrophobicity governs which targeting route is utilized, we used a series of PhoA signal...
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