Article
Defining the role of the Escherichia coli chaperone SecB using comparative proteomics.
The Journal of biological chemistry - 14 Apr 2006
Baars Louise, Ytterberg A Jimmy, Drew David, Wagner Samuel, Thilo Claudia, van Wijk Klaas Jan, de Gier Jan-Willem
Abstract excerpt
To improve understanding and identify novel substrates of the cytoplasmic chaperone SecB in Escherichia coli, we analyzed a secB null mutant using comparative proteomics. The secB null mutation did not affect cell growth but caused significant differences at the proteome level. In the absence of SecB, dynamic protein aggregates containing predominantly secretory proteins accumulated in the cytoplasm. Unprocessed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.