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Article

Toti-/pluripotential Stem Cells and Epigenetic Modifications.

1 Jan 2001

Abstract excerpt

The recent fascinating breakthrough in the area of stem cell research is the successful production of cloned animals via nuclear transplantation of somatic nucleus by intrinsic trans-acting factors of oocytes and trans-differentiation of somatic stem cells from adult organs induced by extrinsic growth factors. During the process of nuclear reprogramming, epigenetic modification of the somatic nuclei must be...

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PMID: 11565807
DOI: 10.1247/csf.26.149

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