Article
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
British journal of pharmacology - 1 Sept 2001
Richter A, Hamann M
Abstract excerpt
1. Recent studies have shown beneficial effects of an adenosine A(2A) receptor agonist in dt(sz) mutant hamsters, an animal model of paroxysmal dystonia, in which stress and consumption of coffee can precipitate dystonic attacks. This prompted us to examine the effects of adenosine receptor agonists and antagonists on severity of dystonia in dt(sz) hamsters in more detail. 2. The non-selective adenosine...
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