Article
Fenitroxon insensitive acetylcholinesterases of the housefly, Musca domestica associated with point mutations.
Insect biochemistry and molecular biology - 1 Sept 2001
Kozaki T, Shono T, Tomita T, Kono Y
Abstract excerpt
The cDNA of AChE in the housefly, Musca domestica, was sequenced and individual flies were genotyped by this gene in an inhibition assay of AChE activity with an organophaspate, fenitroxon. Mutations at Gly(342) and Tyr(407), which are reportedly conserved in resistant strains of Drosophila, were associated with the insensitivity to fenitroxon. Two other mutations, Ile(162) and Val(260), did not have an apparent...
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