Article
Structure-function relationship of the small GTPase rab5.
The Journal of biological chemistry - 15 Nov 1993
Li G, Stahl P D
Abstract excerpt
Overexpression of rab5 via a Sindbis virus vector resulted in a 2-3-fold stimulation of horseradish peroxidase uptake in BHK-21 cells. Based on this functional assay of rab5 activity, we conducted extensive mutational analysis of the structure-function relationship of rab5. A total of 21 deletion and substitution mutations were created and their effects on rab5 activity were examined. Deletion of the entire...
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