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Article

The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish.

Genes & development - 15 Sept 2001

Topczewska J M, Topczewski J, Shostak A, Kume T, Solnica-Krezel L, Hogan B L

Abstract excerpt

Previous studies identified zebrafish foxc1a and foxc1b as homologs of the mouse forkhead gene, Foxc1. Both genes are transcribed in the unsegmented presomitic mesoderm (PSM), newly formed somites, adaxial cells, and head mesoderm. Here, we show that inhibiting synthesis of Foxc1a (but not Foxc1b) protein with two different morpholino antisense oligonucleotides blocks formation of morphological somites, segment...

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Identifiers

PMID: 11562356
DOI: 10.1101/gad.907401
PMCID: PMC312789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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