Article
Genetic analysis of functional domains within the Drosophila LARK RNA-binding protein.
Genetics - 1 Sept 2001
McNeil G P, Schroeder A J, Roberts M A, Jackson F R
Abstract excerpt
LARK is an essential Drosophila RNA-binding protein of the RNA recognition motif (RRM) class that functions during embryonic development and for the circadian regulation of adult eclosion. LARK protein contains three consensus RNA-binding domains: two RRM domains and a retroviral-type zinc finger (RTZF). To show that these three structural domains are required for function, we performed a site-directed...
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