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Article

Cellular requirements for LARK in the Drosophila circadian system.

Journal of biological rhythms - 1 Jun 2012

Sundram Vasudha, Ng Fanny S, Roberts Mary A, Millán Carola, Ewer John, Jackson F Rob

Abstract excerpt

RNA-binding proteins mediate posttranscriptional functions in the circadian systems of multiple species. A conserved RNA recognition motif (RRM) protein encoded by the lark gene is postulated to serve circadian output and molecular oscillator functions in Drosophila and mammals, respectively. In no species, however, has LARK been eliminated, in vivo, to determine the consequences for circadian timing. The present...

Topics

Animals
Animals, Genetically Modified
Circadian Rhythm
Drosophila Proteins
Female
Gene Expression Regulation
Locomotion
Male
Models, Biological
Neurons
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA Interference

RNA Processing, Post-Transcriptional

RNA-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22653887
DOI: 10.1177/0748730412440667
PMCID: PMC4135585

Genes

PDF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-22653887-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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