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Article

The 5-HTTPRS/L polymorphism and aggressive behavior in Alzheimer disease.

Archives of neurology - 1 Sept 2001

Sukonick D L, Pollock B G, Sweet R A, Mulsant B H, Rosen J, Klunk W E, Kastango K B, DeKosky S T, Ferrell R E

Abstract excerpt

BACKGROUND: Aggressive behavior in Alzheimer disease (AD) has been linked to dysfunction of serotonin neurotransmission. Homozygosity for the long variant (*L) of an identified biallelic polymorphism of the serotonin transporter promoter region (5-HTTPR) is associated with increased expression of the transporter protein and increased speed of response to serotonin reuptake inhibitor treatment. OBJECTIVE: To...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11559314
DOI: 10.1001/archneur.58.9.1425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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