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Article

Association between low activity serotonin transporter promoter genotype and early onset alcoholism with habitual impulsive violent behavior.

Molecular psychiatry - 1 Jul 1999

Hallikainen T, Saito T, Lachman H M, Volavka J, Pohjalainen T, Ryynänen O P, Kauhanen J, Syvälahti E, Hietala J, Tiihonen J

Abstract excerpt

A common 44-base pair insertion/deletion polymorphism in the promoter region of the human serotonin transporter (5-HTT) gene has been observed to be associated with affective illness and anxiety-related traits. This biallelic functional polymorphism, designated long (L) and short (S), affects 5-HTT gene expression since the S promoter is less active than the L promoter. Since there is strong evidence of a...

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Source

Identifiers

PMID: 10483057
DOI: 10.1038/sj.mp.4000526

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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