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Article

A kinetic analysis of substrate recognition by uracil-DNA glycosylase from herpes simplex virus type 1.

Nucleic acids research - 15 Sept 2001

Bellamy S R, Baldwin G S

Abstract excerpt

Uracil-DNA glycosylase (UDG) is responsible for the removal of uracil from DNA. It has previously been demonstrated that UDG exhibits some sequence dependence in its activity, although this has not been well characterised. This study has investigated the sequence-dependent activity of UDG from herpes simplex virus type-1 (HSV-1). A more detailed analysis has been possible by using both kinetic and binding assays...

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Identifiers

PMID: 11557818
DOI: 10.1093/nar/29.18.3857
PMCID: PMC55908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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