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Article

SOX Transcription Factors in Endothelial Differentiation and Endothelial-Mesenchymal Transitions

28 Mar 2019

Abstract excerpt

The SRY (Sex Determining Region Y)-related HMG box of DNA binding proteins, referred to as SOX transcription factors, were first identified as critical regulators of male sex determination but are now known to play an important role in vascular development and disease. SOX7, 17, and 18 are essential in endothelial differentiation and SOX2 has emerged as an essential mediator of endothelial-mesenchymal transitions...

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Identifiers

PMID: 30984768
DOI: 10.3389/fcvm.2019.00030

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