Article
Analysis of mutant quantity and quality in human-hamster hybrid AL and AL-179 cells exposed to 137Cs-gamma or HZE-Fe ions.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) - 1 Jan 1998
Waldren C, Vannais D, Drabek R, Gustafson D, Kraemer S, Lenarczyk M, Kronenberg A, Hei T, Ueno A
Abstract excerpt
We measured the number of mutants and the kinds of mutations induced by 137Cs-gamma and by HZE-Fe (56Fe [600 MeV/amu, LET = 190 KeV/micrometer) in standard AL human hamster hybrid cells and in a new variant hybrid, AL-179. We found that HZE-Fe was more mutagenic than 137Cs-gamma per unit dose (about 1.6 fold), but was slightly less mutagenic per mean lethal dose, DO, at both the S1 and hprt- loci of AL cells. On...
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