Article
The role of hyperhomocysteinemia in nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 Dec 2004
Heil S G, De Vriese A S, Kluijtmans L A J, Mortier S, Den Heijer M, Blom H J
Abstract excerpt
Hyperhomocysteinemia (HHcy) is associated with impaired endothelial-dependent vasodilatation and increased risk of atherosclerosis and thrombosis. Here, we summarize some of our previous work on the effect of HHcy on pathways involved in endothelium-dependent vasodilatation, and present new data concerning the endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation. We showed that the 894 G>T...
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