Article
Homocysteine, coagulation, platelet function, and thrombosis.
Seminars in thrombosis and hemostasis - 1 Jan 2000
Coppola A, Davi G, De Stefano V, Mancini F P, Cerbone A M, Di Minno G
Abstract excerpt
Over the last 30 years, a growing body of evidence has documented the role of hyperhomocysteinemia (HHcy) as an independent vascular risk factor. However, the mechanisms through which elevated circulating levels of homocysteine (Hcy) cause vascular injury and promote thrombosis remain elusive. Most findings have been achieved in in vitro studies employing exceedingly high concentrations of Hcy, whereas only a few...
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