Article
In vivo lipid peroxidation and platelet activation in cystic fibrosis.
American journal of respiratory and critical care medicine - 1 Oct 2000
Ciabattoni G, Davì G, Collura M, Iapichino L, Pardo F, Ganci A, Romagnoli R, Maclouf J, Patrono C
Abstract excerpt
F(2)-isoprostanes are bioactive peroxidation products of arachidonic acid whose urinary excretion provides an index of lipid peroxidation in vivo. We tested the hypothesis that formation of F(2)-isoprostanes is altered in patients with cystic fibrosis and contributes to platelet activation and pu...
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