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Article

Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways.

Journal of virology - 1 Oct 2001

Fielding C A, Sandvej K, Mehl A, Brennan P, Jones M, Rowe M

Abstract excerpt

The latent membrane protein 1 (LMP-1) oncogene of Epstein-Barr virus (EBV) is believed to contribute to the development of many EBV-associated tumors, and there is evidence that sequence variation can affect some functions of LMP-1. Most studies have been restricted to the prototype B95.8 LMP-1 gene and genes isolated from EBV of nasopharyngeal carcinoma (NPC) patients. Here, we analyzed the signaling functions...

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Identifiers

PMID: 11533177
DOI: 10.1128/JVI.75.19.9129-9141.2001
PMCID: PMC114482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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