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Article

Evolutionary analysis of LMP-1 genetic diversity in EBV-associated nasopharyngeal carcinoma: Bioinformatic insights into oncogenic potential.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2024

Alanazi Abdullah E, Alhumaidy Aroob Abdullah, Almutairi Hatim, Awadalla Maaweya E, Alkathiri Abdulrahman, Alarjani Modhi, Aldawsari Mesfer Abdullah, Maniah Khalid, Alahmadi Reham M, Alanazi Bader S, Eifan Saleh, Alosaimi Bandar

Abstract excerpt

EBV latent membrane protein 1 (LMP-1) is an important oncogene involved in the induction and maintenance of EBV infection and the activation of several cell survival and proliferative pathways. The genetic diversity of LMP-1 has an important role in immunogenicity and tumorigenicity allowing escape from host cell immunity and more metastatic potential of LMP-1 variants. This study explored the evolutionary of...

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PMID: 38508363
DOI: 10.1016/j.meegid.2024.105586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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