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Semliki Forest virus vectors: efficient vehicles for in vitro and in vivo gene delivery

28 Aug 2001

Abstract excerpt

Rapidly generated high-titer Semliki Forest virus (SFV) vectors can infect numerous mammalian cell lines and primary cell cultures, and result in high levels of transgene expression. SFV-based expression of transmembrane receptors has been characterized by specific ligand-binding activity and functional responses. Adaptation of the SFV technology for mammalian suspension cultures has allowed the production of...

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PMID: 11532440
DOI: 10.1016/s0014-5793(01)02707-7

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