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Article

Anti-ganglioside antibodies in amyotrophic lateral sclerosis revisited.

PloS one - 1 Jan 2015

Kollewe Katja, Wurster Ulrich, Sinzenich Thomas, Körner Sonja, Dengler Reinhard, Mohammadi Bahram, Petri Susanne

Abstract excerpt

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder with typical onset in the 5th- 6th decade of life. The hypothesis of an autoimmune origin of ALS receives less attention today, but immunological phenomena still seem to be involved and mechanisms such as protective autoimmunity may be important. Detection of antibodies against a variety of gangliosides has been repeatedly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25875836
DOI: 10.1371/journal.pone.0125339
PMCID: PMC4397083

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