Antibodies to myelin-associated glycoprotein (anti-Mag) in IgM amyloidosis may influence expression of neuropathy in rare patients.

doi:10.1002/mus.20955

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Article

Antibodies to myelin-associated glycoprotein (anti-Mag) in IgM amyloidosis may influence expression of neuropathy in rare patients.

Muscle & nerve - 1 Apr 2008

Garces-Sanchez Mercedes, Dyck Peter J, Kyle Robert A, Zeldenrust Steven, Wu Yanhong, Ladha Shafeeq S, Klein Christopher J

Abstract excerpt

We have examined whether antibodies to myelin-associated glycoprotein (anti-MAG) influence neuropathy occurrence and phenotype in primary (AL IgM) amyloidosis. Anti-MAG and the cross-reacted sulfoglucuronyl paragloboside antibodies (SGPG) were studied in 46 patients with IgM amyloidosis (21 with polyneuropathy), and 21 matched IgM MGUS (monoclonal gammopathies of undetermined significance) controls without...

Topics

Aged
Aged, 80 and over
Amyloidosis
Ataxia
Autoantibodies
Biopsy
Blotting, Western
Cross Reactions
Female
Globosides
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin M

Male

Middle Aged

Myelin-Associated Glycoprotein

Neural Conduction

Phenotype

Polyradiculoneuropathy

Source

Open in PubMed

Identifiers

PMID: 18236455
DOI: 10.1002/mus.20955

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