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Article

The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.

American journal of human genetics - 1 Oct 2001

Cunningham J M, Kim C Y, Christensen E R, Tester D J, Parc Y, Burgart L J, Halling K C, McDonnell S K, Schaid D J, Walsh Vockley C, Kubly V, Nelson H, Michels V V, Thibodeau S N

Abstract excerpt

A comprehensive analysis of somatic and germline mutations related to DNA mismatch-repair (MMR) genes can clarify the prevalence and mechanism of inactivation in colorectal carcinoma (CRC). In the present study, 257 unselected patients referred for CRC resection were examined for evidence of defective DNA MMR. In particular, we sought to determine the frequency of hereditary defects in DNA MMR in this cohort of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Identifiers

PMID: 11524701
DOI: 10.1086/323658
PMCID: PMC1226064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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