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Article

The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.

American journal of human genetics - 1 Oct 2001

Cunningham J M, Kim C Y, Christensen E R, Tester D J, Parc Y, Burgart L J, Halling K C, McDonnell S K, Schaid D J, Walsh Vockley C, Kubly V, Nelson H, Michels V V, Thibodeau S N

Abstract excerpt

A comprehensive analysis of somatic and germline mutations related to DNA mismatch-repair (MMR) genes can clarify the prevalence and mechanism of inactivation in colorectal carcinoma (CRC). In the present study, 257 unselected patients referred for CRC resection were examined for evidence of defe...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Share to MutL Protein Homolog 1

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Source

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Identifiers

PMID: 11524701
DOI: 10.1086/323658
PMCID: PMC1226064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11524701-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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