Article
Phenotype of cytochrome P450 CYP2D6 in patients with familial adenomatous polyposis.
Methods and findings in experimental and clinical pharmacology - 1 Apr 2001
Slanar O, Perlík F, Jirásek V
Abstract excerpt
This paper describes an attempt to establish the distribution of the oxidative phenotype of sparteine in patients with familial adenomatous polyposis (FAP). The oxidative polymorphism of sparteine was determined in 30 patients with FAP. One hundred and twenty-six normal subjects were examined as a control group. Subjects with urinary metabolic ratios (MR) greater than 20 (the metabolic ratio of...
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