Article
Genetic polymorphisms of CYP2D6 oxidation in patients with inflammatory bowel disease.
Digestive diseases and sciences - 1 Apr 2010
Trzcinski R, Skretkowicz J, Dziki A, Rychlik-Sych M, Baranska M
Abstract excerpt
Inflammatory bowel disease (IBD) consists of ulcerative colitis and Crohn's disease, both of which are associated with increased colorectal cancer risk. The relationship between genetically determined polymorphic metabolism of exogenous substances by oxidation catalyzed by CYP2D6 isoenzyme and susceptibility to cancer has aroused great interest. We determined whether there was an association between...
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