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Article

Metabolic phenotypes and colorectal neoplasia.

Journal of gastroenterology and hepatology - 1 Jan 2000

Fettman M J, Butler R N, McMichael A J, Roberts-Thomson I C

Abstract excerpt

It now appears likely that the development of colonic adenomas and carcinomas involves a series of steps in which environmental or endogenous carcinogens induce or promote neoplasia through the accumulation of multiple, specific genetic mutations. Genetic predisposition to this process may take the form of inherited defects in control of cellular proliferation as in familial polyposis coli, or genetically...

Topics

Acetylation
Acetyltransferases
Adenomatous Polyposis Coli
Colorectal Neoplasms
Dehydroepiandrosterone
Glutathione Peroxidase
Glutathione Transferase
Humans
Hydroxylation
Phenotype
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Characteristics

Xenobiotics

Source

Identifiers

PMID: 1653058
DOI: 10.1111/j.1440-1746.1991.tb01151.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1653058-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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