Article
Inverted repeats as genetic elements for promoting DNA inverted duplication: implications in gene amplification.
Nucleic acids research - 1 Sept 2001
Lin C T, Lin W H, Lyu Y L, Whang-Peng J
Abstract excerpt
Inverted repeats are important genetic elements for genome instability. In the current study we have investigated the role of inverted repeats in a DNA rearrangement reaction using a linear DNA substrate. We show that linear DNA substrates with terminal inverted repeats can efficiently transform Escherichia coli. The transformation products contain circular inverted dimers in which the DNA sequences between...
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