Article
Alcohol hypersensitivity, increased locomotion, and spontaneous myoclonus in mice lacking the potassium channels Kv3.1 and Kv3.3.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 2001
Espinosa F, McMahon A, Chan E, Wang S, Ho C S, Heintz N, Joho R H
Abstract excerpt
The Shaw-like potassium (K(+)) channels Kv3.1 and Kv3.3 are widely coexpressed in distinct neuronal populations in the CNS, possibly explaining the relatively "mild" phenotypes of the Kv3.1 and the Kv3.3 single mutant. Kv3.1-deficient mice show increased cortical gamma- and decreased delta-oscill...
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