Article
Is your ribozyme design really correct?: A proposal of simple single turnover competition assay to evaluate ribozymes.
Bioscience, biotechnology, and biochemistry - 1 Jul 2001
Tanaka T, Inui O, Dohi N, Okada N, Okada H, Kikuchi Y
Abstract excerpt
Today, many nucleic acid enzymes are used in gene therapy and gene regulations. However, no simple assay methods to evaluate enzymatic activities, with which we judge the enzyme design, have been reported. Here, we propose a new simple competition assay for nucleic acid enzymes of different types...
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