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Article

The coming of age of virus-like particle vaccines

6 Mar 2008

Abstract excerpt

Virus-like particles are supra-molecular assemblages, usually icosahedral or rod-like structures. They incorporate key immunologic features of viruses which include repetitive surfaces, particulate structures and induction of innate immunity through activation of pathogen-associated molecular-pattern recognition receptors. They carry no replicative genetic information and can be produced recombinantly in large...

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PMID: 18953718
DOI: 10.1515/bc.2008.064

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