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Article

Kinetic analysis of open- and closed-state inactivation transitions in human Kv4.2 A-type potassium channels.

The Journal of physiology - 15 Aug 2001

Bähring R, Boland L M, Varghese A, Gebauer M, Pongs O

Abstract excerpt

1. We studied the gating kinetics of Kv4.2 channels, the molecular substrate of neuronal somatodendritic A-type currents. For this purpose wild-type and mutant channels were transiently expressed in the human embryonic kidney (HEK) 293 cell line and currents were measured in the whole-cell patch-clamp configuration. 2. Kv4.2 channels inactivated from pre-open closed state(s) with a mean time constant of 959 ms at...

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Identifiers

PMID: 11507158
DOI: 10.1111/j.1469-7793.2001.00065.x
PMCID: PMC2278757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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