Article
Association of an insertion polymorphism of angiotensin-converting enzyme gene with the activity of systemic lupus erythematosus.
Lupus - 1 Jan 1998
Sato H, Akai Y, Iwano M, Kurumatani N, Kurioka H, Kubo A, Yamaguchi T, Fujimoto T, Dohi K
Abstract excerpt
Systemic lupus erythematosus (SLE) shows various clinical manifestations, which are characterized by inflammation in many different organ systems. The cause of SLE is still unclear; however, the immunological abnormalities are considered to be responsible for the pathogenesis of SLE. As angiotensin I-converting enzyme (ACE) has been reported to be associated with various immunological phenomena, we investigated...
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