Article
The Rho1 GTPase-activating protein CgBem2 is required for survival of azole stress in Candida glabrata.
The Journal of biological chemistry - 30 Sept 2011
Borah Sapan, Shivarathri Raju, Kaur Rupinder
Abstract excerpt
Invasive fungal infections are common clinical complications of neonates, critically ill, and immunocompromised patients worldwide. Candida species are the leading cause of disseminated fungal infections, with Candida albicans being the most prevalent species. Candida glabrata, the second/third most common cause of candidemia, shows reduced susceptibility to a widely used antifungal drug fluconazole. Here, we...
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