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Article

Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance.

Cellular signalling - 1 Sept 2001

Bittorf T, Büchse T, Sasse T, Jaster R, Brock J

Abstract excerpt

The transcription factor nuclear factor kappa B (NF-kappaB) has been implicated in the regulation of genes mainly involved in inflammation and immune response. We analysed the role of NF-kappaB in signalling pathways induced by the hematopoietic growth factor erythropoietin (EPO). Our data, obtained by electrophoretic mobility shift assays (EMSA) and reporter gene assays, show that the intracellular domain of the...

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Source

Identifiers

PMID: 11495725
DOI: 10.1016/s0898-6568(01)00189-9

Genes

EPOR
JAK2
EPO
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Activation of the transcription factor NF-kappaB by the erythropoietin receptor: structural requirements and biological significance.PMID 11495725Read ↗

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