Article
Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture.
Spine - 15 Aug 2001
Wang J Y, Baer A E, Kraus V B, Setton L A
Abstract excerpt
STUDY DESIGN: The mRNA levels of aggrecan and collagen were quantified in intervertebral disc cells cultured under three conditions: primary alginate culture, monolayer culture, and re-encapsulation in alginate after monolayer culture. OBJECTIVES: To compare the phenotype of intervertebral disc cells under different culture conditions and to investigate the reversibility of cell phenotype after re-encapsulation...
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