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Article

Radiosensitization by gemcitabine in p53 wild-type and mutant MCF-7 breast carcinoma cell lines.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2001

Robinson B W, Shewach D S

Abstract excerpt

The nucleoside analogue 2',2'-difluoro-2'-deoxycytidine (dFdCyd) is a potent radiosensitizer in several solid tumor cell lines. Radiosensitization has correlated with the dFdCyd-mediated decrease in dATP levels and is S-phase specific. Previous studies suggested that a cell line that was unable to progress through S phase after dFdCyd and radiation was not radiosensitized apparently because of the expression of...

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Identifiers

PMID: 11489842

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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